As the final hour of trading unfolds, momentum is clustering around breakthrough science, regulatory catalysts, strategic commodities, and headline M&A. Here are the stocks commanding attention into the close and potentially into afterhours.

Midday trading is being shaped by a powerful mix of biotech momentum, breakthrough materials science, and strategic buyouts, as investors rotate toward companies delivering tangible catalysts.

Wall Street opens to a convergence of science, scale, and strategic consolidation. From spider silk making mainstream headlines to multibillion-dollar oncology deals and accelerating immunotherapy revenues, today’s tape reflects capital flowing toward platforms with validation.

Kraig Biocraft Laboratories (OTCQB: KBLB) groundbreaking work in commercializing spider silk is featured on the cover of the March 2026 issue of National Geographic magazine.